Hilary Kiyo Finucane is an American computational biologist who is Co-Director of the Program in Medical and Population Genetics at the Broad Institute. Her group combines genetic data with molecular data to understand the origins and mechanisms of disease. WebOct 9, 2024 · Mary L. Finucane is a vice president and banking center manager at First Horizon Bank. She was born and raised in Buffalo, New York, where she earned both …
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WebJun 2, 2024 · Rapid progress of the discovery of genetic loci associated with common, complex diseases has outpaced the elucidation of mechanisms pertinent to disease pathogenesis. To address relevant barriers for coronary artery disease (CAD), we combined genetic discovery analyses with downstream characterization of likely causal variants, … WebSep 28, 2015 · where N is sample size, C indexes categories, (j, C) is the LD score of SNP j with respect to category C (defined as ℓ (j, C) = ∑ k ∈ C r 2 j k ℓ (j, C) = ∑ k ∈ C r j k 2), a is a term that measures the contribution of confounding biases , and if the categories are disjoint, τ C is the per-SNP heritability in category C; if the ...
WebSelected publications and preprints. Masahiro Kanai, Roy Elzur, Wei Zhou, Global Biobank Meta-analysis Initiative, Mark J Daly, Hilary K Finucane (2024) Meta-analysis fine-mapping … WebYakir A Reshef, 1, 2, 3, * Hilary K Finucane, 3 David R Kelley, 4 Alexander Gusev, 5 Dylan Kotliar, 3 Jacob C Ulirsch, 3, 5, 6 Farhad Hormozdiari, 3, 7 Joseph Nasser, 3 Luke O’Connor, 7, 8 Bryce van de Geijn, 7 Po-Ru Loh, 3, 9 Sharon R Grossman, 2, 3 Gaurav Bhatia, 7 Steven Gazal, 7 Pier Francesco Palamara, 3, 7, 10 Luca Pinello, 3, 11, 12 ...
WebBrainstorm Consortium, Verneri Anttila, Brendan Bulik-Sullivan, Hilary K Finucane, Raymond K Walters, Jose Bras, Laramie Duncan, Valentina Escott-Price, Guido J Falcone, Padhraig Gormley, Rainer Malik, Nikolaos A Patsopoulos, Stephan Ripke, Zhi Wei, Dongmei Yu, Phil H Lee, Patrick Turley, Benjamin Grenier-Boley, Vincent Chouraki, Yoichiro Kamatani Show 31 … WebBibTeX @ARTICLE{Reshef11detectingnovel, author = {David N Reshef and Yakir A Reshef and Hilary K Finucane and Sharon R Grossman and Gilean Mcvean and Peter J Turnbaugh and Eric S Lander and Michael Mitzenmacher and ‡ Pardis and C Sabeti}, title = {Detecting novel associations in large data sets}, journal = {science}, year = {2011}, pages = {1518- …
WebJul 7, 2016 · Haplotype phasing is a fundamental problem in medical and population genetics. Phasing is generally performed via statistical phasing within a genotyped cohort, an approach that can attain high accuracy in very large cohorts but attains lower accuracy in smaller cohorts. Here, we instead explore the paradigm of reference-based phasing. We …
WebNov 21, 2024 · Here, we introduce the Global Biobank Meta-analysis Initiative (GBMI) -- a collaborative network of 19 biobanks from 4 continents representing more than 2.1 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWAS generated using harmonized genotypes and … fly fishing shops in baldwin miWebThe Finucane Lab Our group develops and applies new statistical and computational methods for analyzing biological data. Our main focus is on integrating genetic data about disease with molecular data about cell types and biological processes to learn about the causes of disease. We are based at the Broad Institute. fly fishing shops in anchorage alaskaWebNov 25, 2024 · Hilary K. Finucane. Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Schmidt Fellows Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Search for … fly fishing shops in bend oregonWebSteven Gazal 1 2 , Hilary K Finucane 1 2 3 , Nicholas A Furlotte 4 , Po-Ru Loh 1 2 , Pier Francesco Palamara 1 2 , Xuanyao Liu 1 2 , Armin Schoech 1 2 5 , Brendan Bulik-Sullivan 2 6 , Benjamin M Neale 2 6 7 , Alexander Gusev 1 2 , Alkes L Price 1 2 8 greenlaw baptist churchWebCandie Finucan General Manager at Hologic, Inc. Washington, District of Columbia, United States. 9 followers 9 connections green law avocatWebAug 22, 2024 · Meta-analysis is pervasively used to combine multiple genome-wide association studies (GWAS) into a more powerful whole. To resolve causal variants, meta-analysis studies typically apply summary statistics-based fine-mapping methods as they are applied to single-cohort studies. However, it is unclear whether heterogeneous … fly fishing shops in chico caWebHilary K. Finucane's 191 research works with 23,907 citations and 18,703 reads, including: Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated … greenlaw business centre