Phenylglucuronide
WebSep 1, 1990 · Phenylsulfate (35%), phenylglucuronide (15%), and phenylglutathione (12%) represented the major metabolites in hepatocytes from untreated controls. With hepatocytes from MC-treated rats, a pronounced shift from phenylsulfate to phenylglucuronide (increase to 34%) was observed, while the formation of unconjugated phenol, hydroquinone, and ... WebPhenylglucuronide was quantified by its peak area using a linear calibration curve (R 2 > 0.999) made using a commercially available reference compound. Chromatogram peaks …
Phenylglucuronide
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WebJun 6, 2005 · The apparent Vmax for phenylglucuronide formation was equal in RBT and BKT but greater than that observed in LKT. These experiments provide a means to quantify metabolic activation of xenobiotics in fish to compare activation reactions across aquatic species, nd to provide a basis for the prediction of metabolic pathways and rates in fish. WebPhenol and related compounds are toxic agents to which humans are exposed. Analysis of phenolic compounds may be used as an index of exposure. In this report a method for …
WebJun 6, 2005 · The kinetics of phenylglucuronide (PG) in blood and urine of spinally-transected rainbow trout were investigated using microdialysis sampling techniques. … WebMay 15, 1990 · The initial experiments were carried out with p-bromophenol and the desired phenylglucuronide (2b) was isolated in 41% yield, accompanied by 26% of the orthoester …
WebMar 15, 1979 · Phenol is converted by the rat in vivo into the sulphate and glucuronide conjugates. When the intravenously administered dose of 14 C-labelled phenol was increased from 13 to 266 μmol/kg the percentage glucuronidated increased from 28 to 60 per cent of the dose; the percentage sulphated decreased from 72 to 40 per cent. WebDo not exceed recommended dosage; overdose may cause agitation, confusion, slurred speech, and CNS depression. Do not use if blister package has been disturbed or opened. …
WebAug 14, 2013 · Quantification of phenol, phenylglucuronide and phenylsulfate. R 2 > 0.999) prepared from commercially available reference compounds. m/z 173 → 93 and 173 → 80 (Kikuchi et al. 2010R 2 > 0.997) prepared from the in the present study synthesised phenylsulfate. The data were processed with the Analyst software, version 1.5 (Applied …
WebPhenol and related compounds are toxic agents to which humans are exposed. Analysis of phenolic compounds may be used as an index of exposure. In this report a method for analysis of phenol, phenylglucuronide, phenylsulfate, and related mono- and dihydroxybenzenes as their propanoate esters by gas chromatography/mass … lcdc salary texasWeb1) Phenol is well absorbed via gastrointestinal and respiratory tract and the dermal route 2) In body tissues phenol is rapidly distributed 3) It is metabolised to sulfate and glucuronide conjugates 4) Excretion via urine is the main elimination pathway. Key studies (robust study summaries in IUCLID Section 7.1.1) lcdc practice test freeWebCas.No 製品名; 99614-14-9 N-Demethyl Ondansetron 4’-Hydroxy Torsemide-d7 79923-55-0 Ticlopidine N-Oxide Tipranavir-d4 ß-D-Glucuronide lcd controller board shuts offWebQualitative and quantitative analyses of phenol, phenylglucuronide, and phenylsulfate in urine and plasma by gas chromatography/mass spectrometry. 1 Europe PMC requires … lcdc testingWebThus, p-nitrophenylglucuronide, which is a product inhibitor of its own synthesis, had no effect of the rate of synthesis of o-aminophenylglucuronide; and 4-methylumbelliferylglucuronide and phenylglucuronide were competitive inhibitors of the glucuronidation of o-aminophenol but had no effect on that of p-nitrophenol. lcd crystals busted by heatWebAbstract. Phenol and related compounds are toxic agents to which humans are exposed. Analysis of phenolic compounds may be used as an index of exposure. In this report a … lcd crystal arrayWebChloraseptic: 5 sprays onto throat or affected area; may repeat q2h Cheracol, Pain-A-Lay Spray: Spray directly in throat, rinse for 15 seconds, and expectorate; may repeat every 2 hr Cepastat:... lcd ct chest