Tpx2 ground
SpletTPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin … SpletTPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin …
Tpx2 ground
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Splet3 回答. TPG1-ground というところからヤマト運輸の不在票が入っていました。. ここ数日ほかの荷物が把握しきれない程たくさん届く日が続いていました。. しかしこの荷物は … Splet20. apr. 2015 · TPX2 is essential for the formation of an ordered spindle and successful mitosis, 11 and its regulation by importin-α is the major component of RanGTP-mediated spindle assembly (Figure 1), a process on which cancer cells rely more heavily than other cells. 12 As the transport and mitotic roles of importin-α employ two different sites on the …
Splet通过一系列生物信息学方法,我们在陆地棉中鉴定出了41个TPX2基因,所有该家族的成员都包含TPX2结构域。. 通过系统发育树分析,该家族被分成了6个亚家族,亚家族4 (WDLB)成员数量最多,家族1 (MAP20)员数量最少。. 41个陆地棉TPX2基因分布在21条染色体上。. 我们对陆地 … Splet02. nov. 2009 · Abstract. Purpose: The targeting protein for Xklp2 (TPX2) has recently gained attention as a putative oncogene possibly amplified in several human malignancies, including pancreatic adenocarcinoma. In this work, we sought to evaluate the copy number and expression of TPX2 in pancreatic cancer cell lines and tumor tissues and to further …
Splet24. feb. 2024 · TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 …
Splet28. jun. 2011 · Protein Protein TPX2 Gene TPX2 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 790 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Add a publication Entry feedback Function
SpletTPX2 was immunoprecipitated from 1mg of HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate with ab264124 at 0.4µg/mg lysate. Western blot was performed from the immunoprecipitate using ab264124 at 0.1µg/ml. Lane 1: HeLa whole cell lysate 50µg (Input). Lane 2: ab264124 IP in HeLa whole cell lysate. dive shop boise idahoSplet08. feb. 2024 · Results and Discussion The Aurora-A/TPX2 Complex Is Required for NuMA Localization and Spindle Orientation in Cultured Human Cells. In order to investigate whether the role of Aurora-A in spindle orientation requires TPX2-mediated activation, we used clonal U2OS cell lines stably expressing GFP-tagged mouse TPX2 (mTPX2), either … dive shop bermudaSplet25. jun. 2024 · Targeting protein for Xenopus kinesin‑like protein 2 (TPX2) activates Aurora kinase A during mitosis and targets its activity to the mitotic spindle, serving an important role in mitosis. It has been associated with different types of cancer and is considered to promote tumor growth. The aim of the present study was to explore the role of TPX2 in … dive shop boiseSplet14. mar. 2012 · Tpx2 +/ − mice accumulate aneuploidy with age indicating that their tissues are genetically unstable. This feature correlates with increased susceptibility to tumor development, supporting the idea that Tpx2 deregulation might eventually act as a driving force of tumor development by the induction of aneuploidy. ... dive shop boca ratonSplet10. sep. 2024 · Amazon NGO2_GROUND 等. お目当てのワードが出現。 これは、解決か。 一番上に出てきた検索結果は. Amazonの公式ページ. どうやらNGO2は. 岐阜、多治見 … craft beer champaign ilSplet27. jan. 2024 · Since TPX2 function is closely linked to Aurora A (TPX2-Aurora A complex being oncogenic), we undertook a joint computational and experimental approach to predict and validate the effect of withanone (an active anticancer component in i-Extract) on TPX2-Aurora A complex. Results and Discussion Human gene loci, 20q11 and 20q13, that … craft beer channel twitterSplet30. nov. 2011 · Chromosome segregation during mitosis and meiosis relies on the spindle and the functions of numerous microtubule-associated proteins (MAPs). One of the best-studied spindle MAPs is the highly conserved TPX2, which has been reported to have characteristic intracellular dynamics and molecular activities, such as nuclear … dive shop boise id